Protein kinase inhibitor H-7
CAS No. 84477-87-2
Protein kinase inhibitor H-7( -(5-Isoquinolinylsulfonyl)-2-methylpiperazine | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline )
Catalog No. M28552 CAS No. 84477-87-2
Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 78 | Get Quote |
|
| 25MG | 123 | Get Quote |
|
| 50MG | 176 | Get Quote |
|
| 100MG | 257 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameProtein kinase inhibitor H-7
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NoteResearch use only, not for human use.
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Brief DescriptionProtein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
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DescriptionProtein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
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In Vitro——
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In Vivo——
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Synonyms-(5-Isoquinolinylsulfonyl)-2-methylpiperazine | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
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PathwayAngiogenesis
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TargetPKC
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RecptorSmoothened
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Research Area——
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Indication——
Chemical Information
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CAS Number84477-87-2
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Formula Weight291.37
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Molecular FormulaC14H17N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (343.21 mM)
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SMILESO=S(=O)(C1=CC=CC=2C=NC=CC21)N3CCNCC3C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wang Y, et al. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15;7(6):1040-8.
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